October 15, 2025 Program Invited Talks Registration Technical Program Share this page: Twitter Facebook LinkedIn Email By Cristin Merritt At SC25, the Invited Talks will highlight how high performance computing (HPC), artificial intelligence (AI), and related technologies are driving progress across science, engineering, and industry. These sessions bring together leading experts to share their perspectives on how computing continues to ignite new possibilities and shape the future. This year’s program spans national strategies for computing competitiveness, the challenges of big data, and the role of HPC in creativity and research. Talks will feature advances in areas such as space exploration, real-time weather prediction, and AI-driven healthcare at scale—examples of how HPC ignites innovation in diverse domains. The Invited Talks provide an opportunity to see how HPC is being applied in both expected and unexpected ways, fueling discovery and new approaches across disciplines. They are included in the Technical Program registration (in-person and digital). Secure your badge to join these sessions and be part of the conversations shaping the next chapter of computing. Welcoming This Year’s Invited Speakers Tuesday, November 18, 2025 Life SCiences 1:30–2:15 pm CST Enabling Earth-Independence for Human Missions to the Moon and Beyond Alonso Vera NASA Ames 2:15–3 pm CST Nightingale AI – Building Medical Foundation Models at Nation-State Scale Aldo Faisal Imperial College London (UK) / Universität Bayreuth (Germany) Wednesday, November 19, 2025 Creativity 10:30–11:15 am CST High Performance Creativity Lav Varshney Stony Brook University / Kocree, Inc. 11:15 am–12 pm CST Phantoms and Traces: A Field Guide to Non-Referential Data Dietmar Offenhuber Northeastern University Ultrascale Infrastructure 1:30–2:15 pm CST Gigawatt-scale AI Infrastructure: Challenges, Opportunities, and Best Practices Benjamin Treynor Sloss Google LLC 2:15–3 pm CST Nuclear Energy and Large-Scale Computing April Novak University of Illinois at Urbana-Champaign National Strategies 3:30–4:15 pm CST National Supercomputing Mission: Building India’s Self-Reliant HPC Ecosystem Sanjay Wandhekar Centre for Development of Advanced Computing (C-DAC) 4:15–5 pm CST Serving Innovation and Industrial Competitiveness Through Public Infrastructures Sabine Mehr GENCI Thursday, 20 November, 2025 Applications 8:40–9:20 am CST Opportunities in Egocentric Video Understanding Dima Damen University of Bristol 9:20–10:05 am CST Supercomputing the Skies: How GE Aerospace Is Revolutionizing the Future of Flight Trevor Wood GE Aerospace Big Data 10:30–11:15 am CST From Gordon Bell Finalist to the Osaka Expo: The Evolution of Real-Time Forecasting on Fugaku Takemasa Miyoshi RIKEN Center for Computational Science (R-CCS) 11:15 am–12 pm CST Pixels, Petabytes, and Predictions: The Supercomputing Demands of Modern Geospatial AI and How St. Louis Is the Center of Gravity Mark Munsell GeoFuturesSTL